Rectal indomethacin versus intraperitoneal lidocaine for analgesia after laparoscopic cholecystectomy

Background: Visceral and shoulder painare among the most frequent reported pain after laparoscopic cholecystectomy (LC). Objectives: To investigate effectiveness clinical value of rectal indomecthacin and  intraperitoneal lidocaine  for treating cholecystectomy. Patients methods: In Qena university hospital, this prospective randomized comparative study was conducted, 80 patients were scheduled to elective cholecystectomy. Group intraperitonealIP lidocaine (40 patients) received 200 ml saline containing mg 2%lidocaine immediately pneumoperitoneum, total solution sprayed on upper surface liver, right subdiaphragmatic space around site. indomethacin two 100 suppositories 2 hours prior surgery. Results: VAS score significantly lower in indomethacine group ( p =0.03)over 24 postoperative . The pethidine requirements significant mean (34±11.4 mg). Postoperative nausea vomiting less with no statistically difference. Conclusion: preoperative decrease scores analgesics without producing side effects comparing IP LC. Clinical trail .gov ID:NCT04964180